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DeCS
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Descriptor English:
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DNA Gyrase
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Descriptor Spanish:
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Girasa de ADN
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Descriptor Portuguese:
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DNA Girase
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Synonyms English:
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DNA Gyrase A Subunit
DNA Gyrase B Subunit
gyrA Protein
gyrB Protein
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Tree Number:
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D08.811.399.403.741.300.500
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Definition English:
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A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting two A and two B subunits. In the presence of ATP, gyrase is able to convert relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase. |
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History Note English:
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2002; use DNA TOPOISOMERASE (ATP-HYDROLYZING) 1994-2001, use DNA GYRASE 1980-1993; for GYRA PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1992-2001; GYRB PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1991-2001
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Allowable Qualifiers English:
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Record Number:
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36089
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Unique Identifier:
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D027081
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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